OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF

Among other things, the present disclosure provides oligonucleotides and compositions thereof. In some embodiments, provided oligonucleotides and compositions are useful for adenosine modification. In some embodiments, the present disclosure provides methods for treating various conditions, disorder...

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Hauptverfasser: LAMATTINA, Anthony, MARAPPAN, Subramanian, BUTLER, David Charles Donnell, SHIVALILA, Chikdu Shakti, MONIAN, Prashant, IWAMOTO, Naoki, KUMARASAMY, Jayakanthan, YU, Hui, BOULAY, David John, PU, Tom Liantang, SHIMIZU, Mamoru, STANDLEY, Stephany Michelle, GODFREY, Jack David, VARGEESE, Chandra, LU, Genliang, HOSS, Andrew Guzior, KANDASAMY, Pachamuthu, APPONI, Luciano Henrique, YANG, Hailin, DESAI, Jigar
Format: Patent
Sprache:eng
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Zusammenfassung:Among other things, the present disclosure provides oligonucleotides and compositions thereof. In some embodiments, provided oligonucleotides and compositions are useful for adenosine modification. In some embodiments, the present disclosure provides methods for treating various conditions, disorders or diseases that can benefit from adenosine modification.