COMPOUNDS FOR TARGETED PROTEIN DEGRADATION OF KINASES
The present invention relates to bifunctional compounds for targeted kinase degradation, methods for treating diseases or conditions mediated by aberrant kinase activity, and methods for identifying degradable kinases and optimal kinase: scaffold pairs.
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| creator | GRAY, Nathanael S RYU, SeongShick DONOVAN, Katherine FISCHER, Eric S SIM, Taebo BHUNIA, Debabrata BUSHMAN, Jonathan W FERGUSON, Fleur M |
| description | The present invention relates to bifunctional compounds for targeted kinase degradation, methods for treating diseases or conditions mediated by aberrant kinase activity, and methods for identifying degradable kinases and optimal kinase: scaffold pairs. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
| title | COMPOUNDS FOR TARGETED PROTEIN DEGRADATION OF KINASES |
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