ENGINEERED CELLS FOR INCREASED COLLAGEN PRODUCTION

Cells for increased collagen production are engineered by a novel CRISPR cellular engineering process. The process can be carried out using human cells or even patient- harvested cells. Collagen produced by the cells has a low risk of immunogenicity when implanted into human patients compared to col...

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Bibliographische Detailangaben
Hauptverfasser: HOROWITZ, Andrew C, POWELL, Megan Jayne, MASTOVICH, Tim John, RUBERTI, Jeffrey William, FITZGERALD, Michael, GIFFORD, Jessie Lyn
Format: Patent
Sprache:eng
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Zusammenfassung:Cells for increased collagen production are engineered by a novel CRISPR cellular engineering process. The process can be carried out using human cells or even patient- harvested cells. Collagen produced by the cells has a low risk of immunogenicity when implanted into human patients compared to collagen produced by non-human cells. Cell culture media including chemical additives are also provided to have a further positive effect on collagen production.