IMPROVEMENTS IN OR RELATING TO A DEVICE AND METHODS FOR FACILITATING MANIPULATION OF MICRODROPLETS

43A device is provided which comprises: i) a chip comprising a first region for manipulating a plurality of microdroplets; ii) a microdroplet source for providing the microdroplets; 5 iii) a channel having a distal end, which extends in a first direction into the chip, and a proximal end, which is i...

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Bibliographische Detailangaben
Hauptverfasser: SOSNA, Maciej, INGHAM, Richard Jeremy, ISAAC, Thomas Henry, DEACON, William, ATHANASOPOULOU, Evangelia-Nefeli, WAEBER, Andreas Michael
Format: Patent
Sprache:eng
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Zusammenfassung:43A device is provided which comprises: i) a chip comprising a first region for manipulating a plurality of microdroplets; ii) a microdroplet source for providing the microdroplets; 5 iii) a channel having a distal end, which extends in a first direction into the chip, and a proximal end, which is in fluid communication with the microdroplet source; and iv) a pressure source for moving the microdroplets from the microdroplet source along the channel and into the first region of the chip.10 The pressure source is configured to enable the movement of the microdroplets from the microdroplet source into the proximal end of the channel at a first velocity. Furthermore, the distal end of the channel is fluted or blunted such that the microdroplets move from the distal end of the channel into the first region of the chip at a velocity which is lower than the first velocity.15 [Figure 1]