Modification of a nanopore forming protein oligomer

Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising ana...

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Hauptverfasser: MALAVIARACHCHIGE RABEL, Ranga Prabhath, BLACKWELL, Kimberley Emma, KILGOUR, John Joseph, SINGH, Pratik Raj, JAYASINGHE, Lakmal Nishantha, WALLACE, Elizabeth Jayne
Format: Patent
Sprache:eng
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Zusammenfassung:Provided herein is a method of chemically modifying a polypeptide or polynucleotide monomer. The monomer may be a monomer of a protein pore such as a monomeric or oligomeric protein pore. Also disclosed are related monomers and oligomers and methods of using the disclosed pores in characterising analytes.