COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM

COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM

This invention pertains to biotechnology, more specifically to the field of human health. What is described in particular are covalent conjugates of the SARS-CoV-2 receptor binding domain with a carrier protein, the method used to obtain the conjugates, and the vaccine compositions that contain them...

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Hauptverfasser: GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, RAMÍREZ GONZÁLEZ, Ubel Jesús, BOGGIANO AYO, Tammy, OLIVA HERNÁNDEZ, Reynaldo, SANTANA MEDEROS, Darielys, FERNÁNDEZ CASTILLO, Sonsire, VEREZ BENCOMO, Vicente Guillermo, GARCÍA RIVERA, Daniel, RODRÍGUEZ NODA, Laura Marta, VALDÉS BALBÍN, Yury, GARCÍA RICARDO, Manuel
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:This invention pertains to biotechnology, more specifically to the field of human health. What is described in particular are covalent conjugates of the SARS-CoV-2 receptor binding domain with a carrier protein, the method used to obtain the conjugates, and the vaccine compositions that contain them. The vaccine compositions described in the present invention are useful for the prevention of the SARS-CoV-2 infection as they induce a strong response of neutralizing antibodies.