Stable pharmaceutical preparation
A stable pharmaceutical preparation according to the present invention comprises: (A) an antibody or antigen-binding fragment thereof that binds to interleukin-6 receptor; (B) a surfactant; (C) a stabilizing agent; and (D) a buffer. Even in the case of comprising an antibody, and in particular, a hi...
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| Format: | Patent |
| Sprache: | eng |
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| Zusammenfassung: | A stable pharmaceutical preparation according to the present invention comprises: (A) an antibody or antigen-binding fragment thereof that binds to interleukin-6 receptor; (B) a surfactant; (C) a stabilizing agent; and (D) a buffer. Even in the case of comprising an antibody, and in particular, a high concentration of an antibody, the stable pharmaceutical preparation according to the present invention has low viscosity, has excellent long-term storage stability on the basis of excellent stability under accelerated and harsh conditions, and can be administered intravenously or subcutaneously. |
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