Compositions and methods for in vivo generation of car expressing cells

Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.

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Bibliographische Detailangaben
Hauptverfasser:	KOSHY, Sandeep Tharian, JAYASHANKAR, Shyamali, SKEGRO, Darko, MELLES, Yoel, YANG, Jennifer, GRANDA, Brian Walter, DRANOFF, Glenn, BRIDGEMAN, Chris, TREANOR, Louise Mary, GUYOT, Justine, LEE, Cameron Chuck-munn, RAYO, Amy, MILLER, Sandra, CEBE, Regis, PRICE, Andrew Patrick, BROGGI, Maria Anna Sofia, CANHAM, Stephen Michael, APSUNDE, Tushar Dattu, BARDROFF, Michael
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Aspects of this disclosure relate generally to the use of biomaterials for the in vivo generation of CAR expressing cells. In some embodiments, the biomaterials comprise one or more of a cell recruitment composition, a viral vector, and/or a cell activation agent.