Modified insulin and glucokinase nucleic acids for treating diabetes

The present disclosure relates to modified nucleic acid sequences encoding insulin and glucokinase, expression cassettes and delivery vectors comprising the same, and methods for delivery of the same for treating diabetes.

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Bibliographische Detailangaben
Hauptverfasser: GUPTA, Nachi, BOSCH TUBERT, Maria Fatima, JIMENEZ CENZANO, Veronica, SHEN, Weiran, GARCIA MARTINEZ, Miquel
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure relates to modified nucleic acid sequences encoding insulin and glucokinase, expression cassettes and delivery vectors comprising the same, and methods for delivery of the same for treating diabetes.