Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor
The present disclosure refers to a liquid therapeutic hyperimmune globulin composition comprising human plasma-derived immunoglobulin G (IgG) having antibody titre between 250 and 2,500 per mg/mL of IgG and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titer) between 1.5 and 15 per mg...
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creator | ROSA-BRAY, Marilyn AUGER, Charles ORLOVA, Natalia ROMES, Erin VANDEBERG, Peter GAJARDO RODRÍGUEZ, Rodrigo LINDSAY, Myles WELLHOUSE, Andrea JOSE, Marta |
description | The present disclosure refers to a liquid therapeutic hyperimmune globulin composition comprising human plasma-derived immunoglobulin G (IgG) having antibody titre between 250 and 2,500 per mg/mL of IgG and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titer) between 1.5 and 15 per mg/mL of IgG for use in the treatment of coronavirus disease 2019 (COVID-19) in a patient in need thereof. It also refers to a liquid therapeutic or prophylactic hyperimmune immunoglobulin composition comprising human plasma-derived immunoglobulin M (IgM) having a SARS-CoV-2 titre between 2,000 and 17,000 and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titre) between 200 and 70,000, methods for preparing thereof, and the use thereof for the treatment or prophylaxis of COVID-19. Finally, it also refers to a method for obtaining hyperimmune human plasma from a donor for use in the treatment of COVID-19. |
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It also refers to a liquid therapeutic or prophylactic hyperimmune immunoglobulin composition comprising human plasma-derived immunoglobulin M (IgM) having a SARS-CoV-2 titre between 2,000 and 17,000 and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titre) between 200 and 70,000, methods for preparing thereof, and the use thereof for the treatment or prophylaxis of COVID-19. Finally, it also refers to a method for obtaining hyperimmune human plasma from a donor for use in the treatment of COVID-19.</description><language>eng</language><subject>CHEMISTRY ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PEPTIDES ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230202&DB=EPODOC&CC=AU&NR=2021284903A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230202&DB=EPODOC&CC=AU&NR=2021284903A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>ROSA-BRAY, Marilyn</creatorcontrib><creatorcontrib>AUGER, Charles</creatorcontrib><creatorcontrib>ORLOVA, Natalia</creatorcontrib><creatorcontrib>ROMES, Erin</creatorcontrib><creatorcontrib>VANDEBERG, Peter</creatorcontrib><creatorcontrib>GAJARDO RODRÍGUEZ, Rodrigo</creatorcontrib><creatorcontrib>LINDSAY, Myles</creatorcontrib><creatorcontrib>WELLHOUSE, Andrea</creatorcontrib><creatorcontrib>JOSE, Marta</creatorcontrib><title>Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor</title><description>The present disclosure refers to a liquid therapeutic hyperimmune globulin composition comprising human plasma-derived immunoglobulin G (IgG) having antibody titre between 250 and 2,500 per mg/mL of IgG and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titer) between 1.5 and 15 per mg/mL of IgG for use in the treatment of coronavirus disease 2019 (COVID-19) in a patient in need thereof. It also refers to a liquid therapeutic or prophylactic hyperimmune immunoglobulin composition comprising human plasma-derived immunoglobulin M (IgM) having a SARS-CoV-2 titre between 2,000 and 17,000 and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titre) between 200 and 70,000, methods for preparing thereof, and the use thereof for the treatment or prophylaxis of COVID-19. Finally, it also refers to a method for obtaining hyperimmune human plasma from a donor for use in the treatment of COVID-19.</description><subject>CHEMISTRY</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PEPTIDES</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNjb0KwkAQhNNYiPoOC9Zifiy0DKLGwk7rsJq93EFu97i7FD6Br20CFmJlNcN8H8w0eVVPR95Y2zPBuT0BcrMWP9QLPMQ6CSYa4TDuYClqaUAN3Hly6A23EDV5EvUryD2i4VHQXw-6t8jgOgwWQXmxgNAIi58nE4VdoMUnZ8nyeLjuqxU5qSk4fBBTrMtbnuZZvt3s0qLMiv-sN3MmTHQ</recordid><startdate>20230202</startdate><enddate>20230202</enddate><creator>ROSA-BRAY, Marilyn</creator><creator>AUGER, Charles</creator><creator>ORLOVA, Natalia</creator><creator>ROMES, Erin</creator><creator>VANDEBERG, Peter</creator><creator>GAJARDO RODRÍGUEZ, Rodrigo</creator><creator>LINDSAY, Myles</creator><creator>WELLHOUSE, Andrea</creator><creator>JOSE, Marta</creator><scope>EVB</scope></search><sort><creationdate>20230202</creationdate><title>Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor</title><author>ROSA-BRAY, Marilyn ; AUGER, Charles ; ORLOVA, Natalia ; ROMES, Erin ; VANDEBERG, Peter ; GAJARDO RODRÍGUEZ, Rodrigo ; LINDSAY, Myles ; WELLHOUSE, Andrea ; JOSE, Marta</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_AU2021284903A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>2023</creationdate><topic>CHEMISTRY</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PEPTIDES</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><toplevel>online_resources</toplevel><creatorcontrib>ROSA-BRAY, Marilyn</creatorcontrib><creatorcontrib>AUGER, Charles</creatorcontrib><creatorcontrib>ORLOVA, Natalia</creatorcontrib><creatorcontrib>ROMES, Erin</creatorcontrib><creatorcontrib>VANDEBERG, Peter</creatorcontrib><creatorcontrib>GAJARDO RODRÍGUEZ, Rodrigo</creatorcontrib><creatorcontrib>LINDSAY, Myles</creatorcontrib><creatorcontrib>WELLHOUSE, Andrea</creatorcontrib><creatorcontrib>JOSE, Marta</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>ROSA-BRAY, Marilyn</au><au>AUGER, Charles</au><au>ORLOVA, Natalia</au><au>ROMES, Erin</au><au>VANDEBERG, Peter</au><au>GAJARDO RODRÍGUEZ, Rodrigo</au><au>LINDSAY, Myles</au><au>WELLHOUSE, Andrea</au><au>JOSE, Marta</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor</title><date>2023-02-02</date><risdate>2023</risdate><abstract>The present disclosure refers to a liquid therapeutic hyperimmune globulin composition comprising human plasma-derived immunoglobulin G (IgG) having antibody titre between 250 and 2,500 per mg/mL of IgG and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titer) between 1.5 and 15 per mg/mL of IgG for use in the treatment of coronavirus disease 2019 (COVID-19) in a patient in need thereof. It also refers to a liquid therapeutic or prophylactic hyperimmune immunoglobulin composition comprising human plasma-derived immunoglobulin M (IgM) having a SARS-CoV-2 titre between 2,000 and 17,000 and/or a SARS-CoV-2 neutralization activity (IC50 neutralization titre) between 200 and 70,000, methods for preparing thereof, and the use thereof for the treatment or prophylaxis of COVID-19. Finally, it also refers to a method for obtaining hyperimmune human plasma from a donor for use in the treatment of COVID-19.</abstract><oa>free_for_read</oa></addata></record> |
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subjects | CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES |
title | Hyperimmune IgG and/or IgM compositions and method for preparing thereof and method for obtaining hyperimmune human plasma from a donor |
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