Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses

Abstract A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.

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Hauptverfasser: Whitehead, Stephen S, Murphy, Brian R, Lai, Ching-Juh, Blaney Jr., Joseph E, Hanley, Kathyrn A
Format: Patent
Sprache:eng
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Zusammenfassung:Abstract A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.