Double stranded oligonucleotide compositions and methods relating thereto

The present disclosure provides double stranded oligonucleotides, compositions, and methods relating thereto. The present disclosure encompasses the recognition that structural elements of double stranded oligonucleotides, such as base sequence, chemical modifications (

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Bibliographische Detailangaben
Hauptverfasser: IWAMOTO, Naoki, MARAPPAN, Subramanian, VATHIPADIEKAL, Vinod, VARGEESE, Chandra, KANDASAMY, Pachamuthu, BEDEKAR, Mugdha, APPONI, Luciano H, TRIPATHI, Snehlata, LIU, Wei, BUTLER, David
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides double stranded oligonucleotides, compositions, and methods relating thereto. The present disclosure encompasses the recognition that structural elements of double stranded oligonucleotides, such as base sequence, chemical modifications (