Imidazopyrrolopyridine as inhibitors of the JAK family of kinases
Abstract 2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H) yl)cyclohexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, 5 disorders, and conditions mediated by JAK, such as in...
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| creator | Koudriakova, Tatiana Krawczuk, Paul J Seierstad, Mark Kreutter, Kevin D Rizzolio, Michele C Bacani, Genesis M Chai, Wenying Tichenor, Mark S Smith, Russel C Wang, Aihua Leonard, Kristi Venable, Jennifer D |
| description | Abstract 2-((1r,4r)-4-(imidazo[4,5-d]pyrrolo[2,3-b]pyridin-1(6H) yl)cyclohexyl)acetonitrile compounds, pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, 5 disorders, and conditions mediated by JAK, such as inflammatory bowel disease. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | Imidazopyrrolopyridine as inhibitors of the JAK family of kinases |
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