Composition for preventing or treating obesity-related disease containing amphiregulin-specific double-stranded oligonucleotide structure

The present invention relates to: a double-stranded oligonucleotide which can highly specifically and efficiently inhibit amphiregulin expression, preferably a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or a DNA/RNA hybrid; and a use, of a double-stranded o...

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Bibliographische Detailangaben
Hauptverfasser:	KIM, Tae Rim, YUN, Sung Il, KIM, Jangseon, JUNG, Sang Hyuk, LEE, Mi Sun, CHOI, Soonja, SONG, Kang, HWANG, Soo Hyun, PARK, Han-Oh, SON, Seung-Seob, PARK, Jun Hong
Format:	Patent
Sprache:	eng
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to: a double-stranded oligonucleotide which can highly specifically and efficiently inhibit amphiregulin expression, preferably a double-stranded oligonucleotide comprising a sequence in the form of RNA/RNA, DNA/DNA or a DNA/RNA hybrid; and a use, of a double-stranded oligonucleotide structure and nanoparticles comprising the double-stranded oligonucleotide, for preventing or treating obesity.