Novel amorphous active pharmaceutical ingredients

The present invention is directed to a solid and substantially amorphous active pharmaceutical ingredient, to an oral pharmaceutical formulation comprising said substantially amorphous active pharmaceutical ingredient, as well as to a method for the manufacture of the same. The invention is also dir...

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Bibliographische Detailangaben
Hauptverfasser: IVARSSON, Caroline, FAGERBERG, Jonas, ÅSBERG, Peter
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention is directed to a solid and substantially amorphous active pharmaceutical ingredient, to an oral pharmaceutical formulation comprising said substantially amorphous active pharmaceutical ingredient, as well as to a method for the manufacture of the same. The invention is also directed to the use of a particulate anhydrous and substantially amorphous mesoporous magnesium carbonate (MMC) to stabilize an active pharmaceutical ingredient (API).