Hypoxia-inducible factor prolyl hydroxylase inhibitors for treating aging-related conditions

The present disclosure provides a method of treating a condition associated with aging, including a disease or condition selected from anemia, including unexplained anemia of the elderly, spontaneous anemia of aging, and anemia of inflammation in the elderly, sarcopenia, frailty, tissue injury, musc...

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Bibliographische Detailangaben
Hauptverfasser: REBO, Justin, PAN, Yong, FORTNEY, Kristen, LEONG, Peng, MORGEN, Eric, HO, Andrew
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure provides a method of treating a condition associated with aging, including a disease or condition selected from anemia, including unexplained anemia of the elderly, spontaneous anemia of aging, and anemia of inflammation in the elderly, sarcopenia, frailty, tissue injury, muscle injury, and ischemic damage, the method comprising administering to an elderly subject a therapeutically effective amount of a hypoxia-inducible factor prolyl hydroxylase inhibitor.