Methods and systems for converting precursor cells into gastric tissues through directed differentiation

Abstract Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. A...

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Bibliographische Detailangaben
Hauptverfasser: McCracken, Kyle William, Wells, James Macormack
Format: Patent
Sprache:eng
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Zusammenfassung:Abstract Disclosed are methods of inducing formation of a gastric cells and/or a gastric tissue, such as in the form of a gastric organoid. The formation of gastric cells and/or tissue may be carried out by the activating and/or inhibiting of one or more signaling pathways within a precursor cell. Also disclosed are methods for using the disclosed gastric cells, gastric tissues, and/or gastric organoids derived from precursor cells. 117?17R5