Pharmaceutical formulations of Bruton's tyrosine kinase inhibitor

Pharmaceutical formulations of Bruton's tyrosine kinase inhibitor

PHARMACEUTICAL FORMULATIONS OF BRUTON'S TYROSINE KINASE INHIBITOR Abstract 0- FormulationA 25 - --- FormulationB - --- Formulation C --- Formulation D 0 6 12 18 24 Nominal Time Post-Dose (h) Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor -((R)-...

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Bibliographische Detailangaben
Hauptverfasser: CHONG, Ching Wah, KUEHL, Robert, TAN, Heow, ATLURI, Harisha
Format: Patent
Sprache:eng
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:PHARMACEUTICAL FORMULATIONS OF BRUTON'S TYROSINE KINASE INHIBITOR Abstract 0- FormulationA 25 - --- FormulationB - --- Formulation C --- Formulation D 0 6 12 18 24 Nominal Time Post-Dose (h) Described herein are pharmaceutical formulations of Bruton's tyrosine kinase (Btk) inhibitor -((R)-3-(4-amino-3-(4-phenoxyphenyl)-IH-pyrazolo [3,4-d]pyrimidin 1-yl)piperidin-1-yl)prop-2-en--one. Also disclosed are methods of using the Btk inhibitor, alone or in combination with other therapeutic agents, for the treatment of autoimmune diseases or conditions, heteroimmune diseases or conditions, cancer, including lymphoma, and inflammatory diseases or conditions.