P2X7 modulators
The present invention is directed to compounds of Formulas (I, la, Ila and Ilb): o R3 "X Formula (I) & Formula (la) o R3 R6 0 R3 RR N RI N-R 6 Formula (Ila) Formula (lb) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, la, Ila and Ilb). Methods...
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| creator | Alcazar Vaca, Manuel Jesus Allison, Brett D Wall, Jessica L Deng, Xiaohu Andres Gil, Jose Ignacio Mani, Neelakandha S Chrovian, Christa C Swanson, Devin M Coate, Heather R Rech, Jason C Dvorak, Curt A Stenne, Brice M Letavic, Michael A De Angelis, Meri Liang, Jimmy T Soyode-Johnson, Akinola Gelin, Christine F Savall, Brad M |
| description | The present invention is directed to compounds of Formulas (I, la, Ila and Ilb): o R3 "X Formula (I) & Formula (la) o R3 R6 0 R3 RR N RI N-R 6 Formula (Ila) Formula (lb) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, la, Ila and Ilb). Methods of making and using the compounds of Formulas (I, la, Ila and Ilb) are also within the scope of the invention. |
| format | Patent |
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Methods of making and using the compounds of Formulas (I, la, Ila and Ilb) are also within the scope of the invention.</description><language>eng</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2024</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240201&DB=EPODOC&CC=AU&NR=2021236451B2$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20240201&DB=EPODOC&CC=AU&NR=2021236451B2$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>Alcazar Vaca, Manuel Jesus</creatorcontrib><creatorcontrib>Allison, Brett D</creatorcontrib><creatorcontrib>Wall, Jessica L</creatorcontrib><creatorcontrib>Deng, Xiaohu</creatorcontrib><creatorcontrib>Andres Gil, Jose Ignacio</creatorcontrib><creatorcontrib>Mani, Neelakandha S</creatorcontrib><creatorcontrib>Chrovian, Christa C</creatorcontrib><creatorcontrib>Swanson, Devin M</creatorcontrib><creatorcontrib>Coate, Heather R</creatorcontrib><creatorcontrib>Rech, Jason C</creatorcontrib><creatorcontrib>Dvorak, Curt A</creatorcontrib><creatorcontrib>Stenne, Brice M</creatorcontrib><creatorcontrib>Letavic, Michael A</creatorcontrib><creatorcontrib>De Angelis, Meri</creatorcontrib><creatorcontrib>Liang, Jimmy T</creatorcontrib><creatorcontrib>Soyode-Johnson, Akinola</creatorcontrib><creatorcontrib>Gelin, Christine F</creatorcontrib><creatorcontrib>Savall, Brad M</creatorcontrib><title>P2X7 modulators</title><description>The present invention is directed to compounds of Formulas (I, la, Ila and Ilb): o R3 "X Formula (I) & Formula (la) o R3 R6 0 R3 RR N RI N-R 6 Formula (Ila) Formula (lb) The invention also relates to pharmaceutical compositions comprising compounds of Formulas (I, la, Ila and Ilb). 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Methods of making and using the compounds of Formulas (I, la, Ila and Ilb) are also within the scope of the invention.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | P2X7 modulators |
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