Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier
The present invention addresses the problem of providing a carrier and method for simply and efficiently obtaining or removing extracellular membrane 5 vesicles or viruses present in a sample with high purity while keeping the vesicles or viruses intact, or detecting such vesicles or viruses with hi...
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| creator | HANAYAMA, Rikinari NISHIBU, Takahiro IMAWAKA, Naoko NARUSE, Ken |
| description | The present invention addresses the problem of providing a carrier and method for simply and efficiently obtaining or removing extracellular membrane 5 vesicles or viruses present in a sample with high purity while keeping the vesicles or viruses intact, or detecting such vesicles or viruses with high sensitivity. The present invention relates to: "1. a carrier (Tim carrier) with which a protein (Tim protein) selected from T-cell immunoglobulin and mucin domain containing molecule-4 (Tim-4) protein, Tim-3 protein, and Tim-1 protein, is 10 bound; 2. a method for obtaining extracellular membrane vesicles or viruses in a sample; 3. a method for removing extracellular membrane vesicles or viruses in a sample; 4. a method for detecting extracellular membrane vesicles or viruses in a sample; 5. a kit for capturing extracellular membrane vesicles or viruses, wherein the kit includes the Tim carrier; and 6. a kit for capturing 15 extracellular membrane vesicles or viruses, wherein the kit includes a reagent containing the Tim protein and a reagent containing the carrier". |
| format | Patent |
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| language | eng |
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| subjects | BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE |
| title | Tim protein-bound carrier, methods for obtaining, removing and detecting extracellular membrane vesicles and viruses using said carrier, and kit including said carrier |
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