Adeno-associated virus capsid polypeptides and vectors

The present disclosure relates generally to adeno-associated virus (AAV) capsid polypeptides and encoding nucleic acid molecules. The disclosure also relates to AAV vectors comprising the capsid polypeptides, and nucleic acid vectors (e.g. plasmids) comprising the encoding nucleic acids molecules, a...

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Bibliographische Detailangaben
Hauptverfasser: LISOWSKI, Leszek, CABANES CREUS, Marti, ALEXANDER, Ian, HEBBEN, Matthias Charles Jerome
Format: Patent
Sprache:eng
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Zusammenfassung:The present disclosure relates generally to adeno-associated virus (AAV) capsid polypeptides and encoding nucleic acid molecules. The disclosure also relates to AAV vectors comprising the capsid polypeptides, and nucleic acid vectors (e.g. plasmids) comprising the encoding nucleic acids molecules, as well as to host cells comprising the vectors. The disclosure also relates to methods and uses of the polypeptides, encoding nucleic acids molecules, vectors and host cells.