Potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid

Potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid

The present invention relates to potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)- piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid and solvates thereof. The invention further relates to methods of preparation of said potassium salt of 2-[(4S)-8-fluoro-...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: BUSCHMANN, Helmut, CERON BERTRAN, Jordi Carles, GOLDNER, Thomas
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present invention relates to potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)- piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)phenyl]-4H-quinazolin-4-yl]acetic acid and solvates thereof. The invention further relates to methods of preparation of said potassium salt of 2-[(4S)-8-fluoro-2-[4-(3-methoxyphenyl)piperazin-1-yl]-3-[2-methoxy-5-(trifluoromethyl)- phenyl]-4H-quinazolin-4-yl]acetic acid or solvates thereof as well as pharmaceutical compositions comprising said salt.