miRNA-193a for promoting immunogenic cell death

miRNA-193a for promoting immunogenic cell death

The invention relates to the use of miRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a CRT agonist, promoting the cell surface expression of CRT. This allows the advantageous treatment of cancers without or with low surface expression of CRT. The inventi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: JANICOT, Michel, YAHYANEJAD, Sanaz, VAN PINXTEREN, Laurens Adrianus Hendricus, DE GUNST, Matheus Maria, TELFORD, Bryony, SCHAAPVELD, Roeland Quirinus Jozef, VAN DEN BOSCH, Marion, ALEMDEHY, Mir Farshid
Format: Patent
Sprache:eng
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:The invention relates to the use of miRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a CRT agonist, promoting the cell surface expression of CRT. This allows the advantageous treatment of cancers without or with low surface expression of CRT. The invention further relates to compositions comprising the miRNA for use in such treatment.