Solid forms of TTK inhibitor

Abstract The present invention relates to a hydrobromide salt of the compound of formula (1), to process for the preparation of the hydrobromide salt, to pharmaceutical compositions containing the hydrobromide salt, to the use of such a hydrobromide salt in the manufacture of a medicament for use in...

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Bibliographische Detailangaben
Hauptverfasser:	Sampson, Peter Brent, Li, Sze-Wan, Pauls, Heinz W
Format:	Patent
Sprache:	eng
Schlagworte:	AFTER-TREATMENT OF SINGLE CRYSTALS OR A HOMOGENEOUSPOLYCRYSTALLINE MATERIAL WITH DEFINED STRUCTURE APPARATUS THEREFOR CHEMISTRY CRYSTAL GROWTH HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRODUCTION OF A HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE REFINING BY ZONE-MELTING OF MATERIAL SINGLE CRYSTALS OR HOMOGENEOUS POLYCRYSTALLINE MATERIAL WITHDEFINED STRUCTURE SINGLE-CRYSTAL-GROWTH SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS UNIDIRECTIONAL SOLIDIFICATION OF EUTECTIC MATERIAL ORUNIDIRECTIONAL DEMIXING OF EUTECTOID MATERIAL
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Beschreibung
Zusammenfassung:	Abstract The present invention relates to a hydrobromide salt of the compound of formula (1), to process for the preparation of the hydrobromide salt, to pharmaceutical compositions containing the hydrobromide salt, to the use of such a hydrobromide salt in the manufacture of a medicament for use in the treatment of cancer and to methods of treating such diseases in the human or animal body by administering a therapeutically effective amount of such a hydrobromide salt. H $ NH 0 H (I)