TOOTHPASTE FOR DELIVERING ALLERGENS TO ORAL MUCOSA

Pro-toothpaste compositions formulated to receive a volume of allergen solution to provide toothpastes that exhibit efficacy for oral mucosal immunotherapy (OMIT) and acceptable consumer and product stability properties, along with kits of pro-toothpaste, allergen/extracts of allergens, and optionally compounding means and/or specialized toothbrushes are provided. Toothpastes suitable and effective for OMIT and methods for managing allergic symptoms and for reducing risk of allergy in people without symptoms employing the pro-toothpastes, toothpastes and kits of the invention are also disclosed. See Fig. 1. WO 2015/042402 PCT/US2014/056562 House Dustmite Extract aan xe) () x :k -G 9 oG