MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

MODULATOR OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR, PHARMACEUTICAL COMPOSITIONS, METHODS OF TREATMENT, AND PROCESS FOR MAKING THE MODULATOR

Abstract Compounds of Formula (I): )S 0 0 x y 1 N (R), R1 (R3 (R4)(, pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: KHATUYA, Haripada, YOUNG, Tomothy John, HADIDA RUAH, Sara Sabina, FERRIS, Lori Ann, MCCARTNEY, Jason, CLEVELAND, Thomas, KANG, Ping, KESHAVARZ-SHOKRI, Ali, GROSS, Raymond Stanley, STAVROPOULOS, Kathy, ALCACIO, Timothy, HUGHES, Robert M, PIERRE, Fabrice Jean Denis, KRENITSKY, Paul John, ANGELL, Paul Timothy, GROOTENHUIS, Peter Diederik Jan, BAEK, Minson, SHI, Yi, SHRESTHA, Muna, CLEMENS, Jeremy J, ZHOU, Jinglan, ANDERSON, Corey, PARASELLI, Prasuna, MILLER, Mark Thomas, SIESEL, David Andrew, VAN GOOR, Fredrick F, HSIA, Clara Kuang-Ju, GULEVICH, Anton, TERMIN, Andreas P, UY, Johnny, ABELA, Alexander Russell, JOSHI, Pramond Virupax
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract Compounds of Formula (I): )S 0 0 x y 1 N (R), R1 (R3 (R4)(, pharmaceutically acceptable salts thereof, deuterated derivatives of any of the foregoing, and metabolites of any of the foregoing are disclosed. Pharmaceutical compositions comprising the same, methods of treating cystic fibrosis using the same, and methods for making the same are also disclosed. Also disclosed are solid state forms of Compound 1 and salts and solvates thereof.