Neisseria meningitidis compositions and methods thereof

In one aspect, the invention relates to an isolated polypeptide comprising an amino acid sequence that is at least 95% identical to SEQ ID NO: 71. In another 5 aspect, the invention relates to an immunogenic composition including an isolated non-lipidated, non-pyruvylated ORF2086 polypeptide from Ne...

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Hauptverfasser: Hoiseth, Susan Kay, Anderson, Annaliesa Sybil, Moran, Justin Keith, Jansen, Kathrin Ute, Ruppen, Mark E
Format: Patent
Sprache:eng
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Zusammenfassung:In one aspect, the invention relates to an isolated polypeptide comprising an amino acid sequence that is at least 95% identical to SEQ ID NO: 71. In another 5 aspect, the invention relates to an immunogenic composition including an isolated non-lipidated, non-pyruvylated ORF2086 polypeptide from Neisseria meningitidis serogroup B, and at least one conjugated capsular saccharide from a meningococcal serogroup.