Carbidopa and L-dopa prodrugs and their use to treat Parkinson's disease

CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE Abstract The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's dise...

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Hauptverfasser: Henry, Rodger F, Ho, Raimundo, Huang, Ye, Dempah, Kassibla E, Chan, Vincent S, Cardinal-David, Benoit, Wang, Zhi, Zhang, Geoff G, Stella, Valentino J, Huters, Alexander D, Krabbe, Scott W, Lao, Yanbin, Mayer, Peter T, Enright, Brian P, Lou, Xiaochun, Mackey, Sean E, Matulenko, Mark A, Stambuli, James, Miller, Christopher P, Voight, Eric A, Klix, Russell C, Kym, Philip R
Format: Patent
Sprache:eng
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Zusammenfassung:CARBIDOPA AND L-DOPA PRODRUGS AND THEIR USE TO TREAT PARKINSON'S DISEASE Abstract The present disclosure relates to (a) carbidopa prodrugs, (b) pharmaceutical combinations and compositions comprising a carbidopa prodrug and/or an L-dopa prodrug, and (c) methods of treating Parkinson's disease and associated conditions comprising administering a carbidopa prodrug and an L-dopa prodrug to a subject with Parkinson's disease.