Crystalline forms of (S) 2 ethylbutyl 2 (((S) (((2R,3S,4R,5R) 5 (4aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4- dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

Crystalline forms of (S) 2 ethylbutyl 2 (((S) (((2R,3S,4R,5R) 5 (4aminopyrrolo[2,1-f] [1,2,4]triazin-7-yl)-5-cyano-3,4- dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy)phosphoryl)amino)propanoate

Abstract The present invention relates to novel salts and crystalline forms of (S)-2-ethylbutyl-2-(((S)-(((2R,3S,4R,5R)-5 (4-aminopyrrolo[2,1-fl[1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy)phosphoryl)amino)propanoate (Formula I) for use in treating viral infections...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Carra, Ernest A, Brak, Katrien, Heumann, Lars V, Larson, Nate
Format: Patent
Sprache:eng
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Abstract The present invention relates to novel salts and crystalline forms of (S)-2-ethylbutyl-2-(((S)-(((2R,3S,4R,5R)-5 (4-aminopyrrolo[2,1-fl[1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2 yl)methoxy)(phenoxy)phosphoryl)amino)propanoate (Formula I) for use in treating viral infections. In some embodiments, the viral infection is caused by a virus selected from the group consisting of Arenaviridae, Coronaviridae, Filoviridae, Flaviviridae, and Paramyxoviridae. FormuilaI