MULTISPECIFIC NKp46 BINDING PROTEINS

EDITORIAL NOTE APPLICATION NUMBER - 2021200972 Please note: Abstract page 122 should be numbered 118. Multispecific proteins that bind and specifically redirect NK cells to lyse a target cell of interest are provided without non-specific activation of NK cells in absence of target cells. The protein...

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Bibliographische Detailangaben
Hauptverfasser: GAUTHIER, Laurent, ANCERIZ, Nadia, MOREL, Ariane, ROSSI, Benjamin
Format: Patent
Sprache:eng
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Zusammenfassung:EDITORIAL NOTE APPLICATION NUMBER - 2021200972 Please note: Abstract page 122 should be numbered 118. Multispecific proteins that bind and specifically redirect NK cells to lyse a target cell of interest are provided without non-specific activation of NK cells in absence of target cells. The proteins have utility in the treatment of disease, notably cancer or infectious disease.