Bromodomain inhibitors

The present invention provides for compounds of formula (I) NH'R1 x1 ? OH (I) wherein R, R2, R3, R4, RX', and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, includ...

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Bibliographische Detailangaben
Hauptverfasser:	LIU, Dachun, LI, Bing, HASVOLD, Lisa A, WANG, Le, SCHRIMPF, Michael, SHEPPARD, George S, PRATT, John, FIDANZE, Steven D, MCDANIEL, Keith F
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides for compounds of formula (I) NH'R1 x1 ? OH (I) wherein R, R2, R3, R4, RX', and X2 have any of the values defined in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cancer, and AIDS. Also provided are pharmaceutical compositions comprising compounds of formula (I).