The invention provides a process of using sterile techniques to combine precise doses of dry powders such as probiotics with liquids of different viscosities without exposure to atmospheric, hand-borne and exhaled breath pathogens in locations exposed to such risks including Neonatal Intensive Care Units, Special Care Units, Maternity Units and ICUs where hygiene standards are facing increasingly challenging times associated with pandemics

Abstract The invention provides a process of making a selectively breakable seal that allows using sterile techniques to combine precise doses of dry powders such as probiotics with liquids of different viscosities without exposure to atmospheric, hand-borne and exhaled breath pathogens and subsequent treatment of diarrhea, necrotising enterocolitis, or allergic diseases in infants. b ( a f d Figure 1 Figure 2 Figure 3 Figure 4 Figure 5