Diacylglycerol kinase modulating compounds

The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.

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Hauptverfasser: ZHU, Qingming, GRAUPE, Michael, NAKAI, Ryoko, PATEL, Leena, MATSUMOTO, Hirokazu, PUGH, Catherine, GUERRERO, Juan, HOLMBO, Stephen, WATKINS, Will, SAWA, Masaaki, CODELLI, Julian A, MEDLEY, Jonathan William, MOAZAMI, Yasamin, XU, Jie, JACOBSEN, Jesse, YEUNG, Suet C, LAD, Latesh, ARAI, Mai, WEAVER, Heath A, KOBAYASHI, Tetsuya, HU, Eric
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creator ZHU, Qingming
GRAUPE, Michael
NAKAI, Ryoko
PATEL, Leena
MATSUMOTO, Hirokazu
PUGH, Catherine
GUERRERO, Juan
HOLMBO, Stephen
WATKINS, Will
SAWA, Masaaki
CODELLI, Julian A
MEDLEY, Jonathan William
MOAZAMI, Yasamin
XU, Jie
JACOBSEN, Jesse
YEUNG, Suet C
LAD, Latesh
ARAI, Mai
WEAVER, Heath A
KOBAYASHI, Tetsuya
HU, Eric
description The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.
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subjects CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title Diacylglycerol kinase modulating compounds
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