Diacylglycerol kinase modulating compounds

The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.

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Bibliographische Detailangaben
Hauptverfasser: ZHU, Qingming, GRAUPE, Michael, NAKAI, Ryoko, PATEL, Leena, MATSUMOTO, Hirokazu, PUGH, Catherine, GUERRERO, Juan, HOLMBO, Stephen, WATKINS, Will, SAWA, Masaaki, CODELLI, Julian A, MEDLEY, Jonathan William, MOAZAMI, Yasamin, XU, Jie, JACOBSEN, Jesse, YEUNG, Suet C, LAD, Latesh, ARAI, Mai, WEAVER, Heath A, KOBAYASHI, Tetsuya, HU, Eric
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides diacylglycerol kinase modulating compounds, and pharmaceutical compositions thereof, for treating cancer, including solid tumors, and viral infections, such as HIV or hepatitis B virus infection. The compounds can be used alone or in combination with other agents.