Preparation of Trifarotene and intermediates and polymorphs thereof

Preparation of Trifarotene and intermediates and polymorphs thereof

The present disclosure provides a process for the preparation of Trifarotene. The disclosure also provides novel intermediates in the process described herein. Also provided are novel polymorphs of Trifarotene.

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Bibliographische Detailangaben
Hauptverfasser: SIMHON, Elliot, AVRAMOFF, Avi, DUSHKIN, Andrey, PIZEM, Hillel, SHEFFER DEE-NOOR, Shani, KAFTANOV, Yulia, OZER, Ilana
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure provides a process for the preparation of Trifarotene. The disclosure also provides novel intermediates in the process described herein. Also provided are novel polymorphs of Trifarotene.