Treatment of lower airways disorders

A method for treating an inflammatory disorder of the lower airways in a human subject in need thereof is described, including administering an effective amount of anakinra directly to the lower airways in the human subject; where the effective amount of anakinra is from about 0.1 mg to about 200 mg...

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Hauptverfasser: LORTIE, Brian A, SYMONDS, William, WRING, Stephen A, PALACIOS, Michelle, BISHOP, James P, KILGORE, Kenneth S, HASTEDT, Jayne E, BARANOWSKI, Lyn A, CRIZER, Katelyn R
Format: Patent
Sprache:eng
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Zusammenfassung:A method for treating an inflammatory disorder of the lower airways in a human subject in need thereof is described, including administering an effective amount of anakinra directly to the lower airways in the human subject; where the effective amount of anakinra is from about 0.1 mg to about 200 mg per day; and where the inflammatory disorder is selected from the group consisting of a toxic-inhalation lung injury, pulmonary langerhans cell histiocytosis, non-cystic fibrosis bronchiectasis, diffuse panbronchiolitis, acute respiratory distress syndrome (ARDS), reactive airways dysfunction syndrome (RADS), bronchiolitis obliterans organizing pneumonia (BOOP), and pneumonitis.