1,2,4-oxadiazole derivatives as liver X receptor agonists

1,2,4-oxadiazole derivatives as liver X receptor agonists

Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition...

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Bibliographische Detailangaben
Hauptverfasser: LINKENS, Kathryn Taylor, SMITH, Jeffrey, SHAW, Duncan, FLYER, Alec Nathanson, HARDY, Declan, MA, Fupeng, BOSS, Kelly D, LOREN, Jon Christopher, FAN, Yi, MOLTENI, Valentina, SOLOVAY, Catherine Fooks, HUANG, Zhihong
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided herein are compounds and pharmaceutical compositions useful for treating meibomian gland dysfunction (MGD), comprising administering to a subject in need thereof a therapeutically effective amount of a compound of Formula (I) or a compound of Formula (I'), or pharmaceutical composition described herein.