Normalisation method and normalisation system for a dried blood matrix

The present invention relates to a normalisation method for a dried blood matrix, said method comprising the steps: providing the dried blood matrix; extracting at least one analyte from a first portion of the dried blood matrix and haemoglobin from a second portion of the dried blood matrix; quanti...

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Bibliographische Detailangaben
Hauptverfasser:	KRÜGER, Nancy, BÖHRINGER, Falko, BUCHHOLZ, Tina, BLANKENSTEIN, Oliver
Format:	Patent
Sprache:	eng
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
Online-Zugang:	Volltext bestellen
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Beschreibung
Zusammenfassung:	The present invention relates to a normalisation method for a dried blood matrix, said method comprising the steps: providing the dried blood matrix; extracting at least one analyte from a first portion of the dried blood matrix and haemoglobin from a second portion of the dried blood matrix; quantitatively analysing the at least one extracted analyte and the extracted haemoglobin; determining a concentration of the at least one analyte in the first portion of the dried blood matrix and a concentration of the haemoglobin in the second portion of the dried blood matrix; deriving the haematocrit of the second portion of the dried blood matrix on the basis of the concentration of the haemoglobin; and calculating a normalisation factor on the basis of the determined haematocrit in order to normalise the concentration of the at least one analyte in the first portion of the dried blood matrix. The invention also relates to a normalisation device (10) for performing a method according to the invention.