RI-labeled humanized antibody

This RI-labeled anti-MUC5AC humanized antibody is a complex of a radionuclide-chelated chelating agent and an antibody (the radionuclide is a metal nuclide that emits α-rays or positrons, and the antibody is a humanized antibody that binds specifically to MUC5AC) and is very useful in the treatment...

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Bibliographische Detailangaben
Hauptverfasser:	KOBASHI, Nobuya, NAKATA, Norihito, MATONO, Mitsuhiro, OCHIAI, Yasushi, MURAKAMI, Takayuki, SHOYAMA, Yoshinari
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	This RI-labeled anti-MUC5AC humanized antibody is a complex of a radionuclide-chelated chelating agent and an antibody (the radionuclide is a metal nuclide that emits α-rays or positrons, and the antibody is a humanized antibody that binds specifically to MUC5AC) and is very useful in the treatment and/or diagnosis of diseases in which MUC5AC is overexpressed, especially cancer, due to excellent specificity for MUC5AC and ability to accumulate in tumors.