Essentially sodium-free effervescent solid pharmaceutical compositions

Essentially sodium-free effervescent solid pharmaceutical compositions The present invention relates to an effervescent solid pharmaceutical composition, which is essentially free of sodium content, comprising: a therapeutically effective amount of an active pharmaceutical ingredient; one or more ph...

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Hauptverfasser: FORMOSA MÁRQUEZ, Xavier, SUÑÉ NEGRE, José María, NAIDU, Venkataramana, CHAUHAN, Manishkumar Jayantibhai, ROIG CARRERAS, Manuel, SUÑÉ POU, Marc, PATEL, Manish Mavjibhai
Format: Patent
Sprache:eng
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Zusammenfassung:Essentially sodium-free effervescent solid pharmaceutical compositions The present invention relates to an effervescent solid pharmaceutical composition, which is essentially free of sodium content, comprising: a therapeutically effective amount of an active pharmaceutical ingredient; one or more pharmaceutically acceptable alkaline earth metal carbonates or hydrogencarbonates in an amount from 1 to 31% by weight of the composition; and one or more pharmaceutically acceptable acids, pharmaceutically acceptable acid salts, or alternatively, a mixture thereof, in an amount from 2 to 62% by weight of the composition; together with one or more pharmaceutically acceptable excipients or carriers; wherein, the total content of the ion sodium in the effervescent solid pharmaceutical composition is equal to or lower than 1 mmol. It also relates to processes for its preparation and its use in therapy.