AZA-quinoline compounds and uses thereof

Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, Ji Yue (Jeff), ZHAO, Kehao, LI, Ling, LIU, Kevin Kun Chin, DAI, Xuan, MI, Yuan, YAN, Xiaoxia, PAPILLON, Julien, YU, Zhengtian, MAK, Sing Yeung Frankie, DORE, Michael, GU, Xiang-Ju Justin, OYANG, Counde, QI, Wei (Vicky)
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided aza-quinoline compounds of Formula (I), pharmaceutical compositions comprising such compounds; and the use of such compounds for treating a disease or condition mediated by Enhancer of Zeste Homolog 2 (EZH2), Polycomb Repressive Complex 2 (PRC2), or a combination thereof.