5-heteroaryl-pyridin-2-amine confounds as neuropeptide ff receptor antagonists

The present invention relates to novel aminopyridine derivatives of the general formula (I) and pharmaceutical compositions comprising these compounds, as well as their therapeutic use, particularly as neuropeptide FF (NPFF) receptor antagonists, including, e.g., for the treatment or prevention of p...

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Bibliographische Detailangaben
Hauptverfasser: SCHANN, Stephan, FER, Mickaël, DOEBELIN, Christelle, MAYER, Stanislas
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel aminopyridine derivatives of the general formula (I) and pharmaceutical compositions comprising these compounds, as well as their therapeutic use, particularly as neuropeptide FF (NPFF) receptor antagonists, including, e.g., for the treatment or prevention of pain, opioid-induced hyperalgesia, or addiction.