Humanized anti-IL17A antibody and use thereof

Provided are a humanized monoclonal antibody binding to IL17A and a nucleic acid sequence (comprising heavy/light chain variable regions) encoding the antibody, a vector containing the nucleic acid sequence, a pharmaceutical composition and a kit. The monoclonal antibody can specifically bind to an...

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Bibliographische Detailangaben
Hauptverfasser: SUN, Chunyun, XIE, Liangzhi, LI, Jing, LIU, Tianjiao
Format: Patent
Sprache:eng
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Zusammenfassung:Provided are a humanized monoclonal antibody binding to IL17A and a nucleic acid sequence (comprising heavy/light chain variable regions) encoding the antibody, a vector containing the nucleic acid sequence, a pharmaceutical composition and a kit. The monoclonal antibody can specifically bind to an IL17A protein with a high affinity, has a stronger ability to block the binding of IL17A and IL17A/F to the receptor IL17RA, and can be used for treating psoriasis, etc.