Polyvalent immunogenicity composition for human papillomavirus
Disclosed is a polyvalent human papillomavirus (HPV) immunogenicity composition for preventing disease or infections related to HPV. The polyvalent HPV immunogenicity composition contains: an HPV virus-like particle formed from assembling L1 proteins of HPV type 6, type 11, type 16, type 18, type 31...
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Zusammenfassung: | Disclosed is a polyvalent human papillomavirus (HPV) immunogenicity composition for preventing disease or infections related to HPV. The polyvalent HPV immunogenicity composition contains: an HPV virus-like particle formed from assembling L1 proteins of HPV type 6, type 11, type 16, type 18, type 31, type 33, type 45, type 52, and type 58; and one or more HPV virus-like particles formed from assembling L1 proteins of other pathogenic HPV types. In one embodiment, the one or more other pathogenic HPV types are selected from HPV type 35, type 39, type 51, type 56, or type 59. In one embodiment, at least one of the described HPV virus-like particles is a chimeric HPV virus-like particle, the chimeric HPV virus-like particle containing one or more chimeric HPV L1 proteins. |
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