Neurostimulation using endoluminal focussed ultrasound

An endoluminal neurostimulation device includes a plurality of ultrasound transducer elements forming a transducer array. The plurality of transducer elements are provided on or in a substrate layer that is adapted for endoluminal delivery to a deployment site in a lumen of a subject. The transducer elements are operable to focus acoustic energy emitted from the transducer array by controlling one or more of the phase delay and time delay of ultrasound signals emitted from the plurality of transducer elements such that acoustic energy emitted from the transducer array is maximised at a neuronal target near the deployment site to achieve stimulation thereof.