Detection of colorectal cancer

The present disclosure provides, among other things, methods for colorectal cancer screening and compositions related thereto. In various embodiments, the present disclosure provides methods for colorectal cancer screening that include analysis of methylation status of one or more methylation biomar...

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Bibliographische Detailangaben
Hauptverfasser: KNAP, Primoz, MARTINEZ-BAREA, Juan, BITENC, Marko, KRUUSMAA, Kristi, HENSE, Christian, CHERSICOLA, Marko
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present disclosure provides, among other things, methods for colorectal cancer screening and compositions related thereto. In various embodiments, the present disclosure provides methods for colorectal cancer screening that include analysis of methylation status of one or more methylation biomarkers, and compositions related thereto. In various embodiments, the present disclosure provides methods for colorectal cancer screening that include screening methylation status of one or more methylation biomarkers in cfDNA, e.g., in ctDNA. In various embodiments, the present disclosure provides methods for colorectal cancer screening that include screening methylation status of one or more methylation biomarkers in cfDNA, e.g., in ctDNA, using MSRE-qPCR.