Substituted heterocyclic amide compound and preparation method therefor and pharmaceutical use thereof

Substituted heterocyclic amide compound and preparation method therefor and pharmaceutical use thereof

Provided are a substituted heterocyclic amide compound having a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use of same in the preparation of a drug for...

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Bibliographische Detailangaben
Hauptverfasser: HU, Gang, ZHOU, Fusheng, XU, Xiaoming, DING, Qian, LAN, Jiong, ZHANG, Leitao, LIU, Zhubo, LV, Qiang, XIE, Fubo, ZHENG, Biao
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided are a substituted heterocyclic amide compound having a selective inhibitory effect on RIPK1, and a pharmaceutically acceptable salt, a stereoisomer, a solvate or a prodrug thereof, and a pharmaceutical composition containing the compound, and the use of same in the preparation of a drug for treating RIPK1-related diseases or conditions.