Novel lactic acid bacteria strains that promote the absorption of calcium - peptides and associated products

The present invention relates to the Lactobacillus helveticus VF45A strain filed with the CNCM under the order number CNCM-l-5300, mutants and variants thereof having at least 80% identity, preferably at least 90% identity, preferably at least 95% identity with the genome of said VF45A strain and ca...

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Bibliographische Detailangaben
Hauptverfasser:	DRIDER, Djamel, FLAHAUT, Christophe, CUDENNEC, Benoit, DHULSTER, Pascal, FREMONT, Marc, RAVESCHOT, Cyril, COUTTE, François, VAEREMANS, Maxime
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FOODS OR FOODSTUFFS FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BYSUBCLASSES A23B - A23J HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OFNUTRITIVE QUALITIES, PHYSICAL TREATMENT THEIR TREATMENT, NOT COVERED BY OTHER CLASSES VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to the Lactobacillus helveticus VF45A strain filed with the CNCM under the order number CNCM-l-5300, mutants and variants thereof having at least 80% identity, preferably at least 90% identity, preferably at least 95% identity with the genome of said VF45A strain and capable of producing at least one peptide corresponding to the SEQ ID 1 to SEQ ID NO 43 sequences and/or capable of reducing the pH of milk, in particular cow's milk and in particular skimmed cow's milk, by anaerobic fermentation, to a value substantially equal to or less than 3.36, in particular equal to 3.32 after 48 hours of fermentation at 37°C. The present invention also relates to isolated peptides that may be obtained by fermentation of milk, in particular cow's milk, by the aforementioned strain. The present invention also relates to the Lactobacillus helveticus VFH049 strain filed with the CNCM under the order number CNCM-l-5403 and mutants and variants thereof having at least 80% identity, preferably at least 90% identity, preferably at least 95% identity with the genome of said VFHD49 strain and capable of producing at least one peptide corresponding to the SEQ ID 44 to SEQ ID NO 86 sequences and/or capable of increasing the intestinal absorption of calcium. The present invention also relates to an isolated peptide, a mixture of peptides and associated products and compositions and the Lactobacillus delbrueckii ssp. bulgaricus VF50b strain filed with the CNCM under the order number CNCM-l-5316 and mutants and variants thereof having at least 80% identity, preferably at least 90% identity, preferably at least 95% identity with the genome of said VF50b strain and capable of producing at least one peptide corresponding to the SEQ ID 87 to SEQ ID NO 199 sequences and/or capable of increasing the intestinal absorption of calcium. The present invention also relates to an isolated peptide, a mixture of peptides and associated pharmaceutical and food compositions.