NOVEL NATURAL PROTEIN AND APPLICATION THEREOF

Provided is a secretory protein sDSS1 of a higher primate. The sDSS1 protein can bind, under non-enzymatic conditions, with an oxidized protein to form a polymer, or bind with an AP polypeptide to reduce the formation of an AP oligomer. The sDSS1 protein can shield against cytotoxicity induced by an...

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Bibliographische Detailangaben
Hauptverfasser:	Wan, Jia, Fu, Jingpeng, Zhang, Yinghao
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided is a secretory protein sDSS1 of a higher primate. The sDSS1 protein can bind, under non-enzymatic conditions, with an oxidized protein to form a polymer, or bind with an AP polypeptide to reduce the formation of an AP oligomer. The sDSS1 protein can shield against cytotoxicity induced by an oxidized protein, AP oligomer, amylin oligomer, or glycosylated protein. The protein can be used to prevent and treat a disease caused by accumulation of an oxidized protein, glycoprotein, AP protein, or amylin, or by the generation or accumulation of another pathogenic protein with a similar property.