Composition comprising cyclodextrin and budesonide derivatives for the treatment and prophylaxis of pulmonary inflammations

The present invention relates to novel and useful pharmaceutical compositions formulated with a cyclodextrin compound and a budesonide derivative for the treatment and/or prevention of pulmonary inflammatory disease. The present invention also relates to a novel and useful analytical technique for t...

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Bibliographische Detailangaben
Hauptverfasser: DUFOUR, Gilles, MAES, Paul, DE TULLIO, Pascal, CATALDO, Didier, EVRARD, Brigitte
Format: Patent
Sprache:eng
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Beschreibung
Zusammenfassung:The present invention relates to novel and useful pharmaceutical compositions formulated with a cyclodextrin compound and a budesonide derivative for the treatment and/or prevention of pulmonary inflammatory disease. The present invention also relates to a novel and useful analytical technique for the detection and the quantification of HP-p-CD in solution. More specifically, the present invention relates to the use of a validated 1H NMR analysis for the detection and quantification of cyclodextrins directly in pharmaceutical formulations without any extraction or separation steps for liquid formulations.